Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Type of information:
other: read across based on OECD Toolbox v3.4
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see attached OECD Toolbox study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
GLP compliance:
not specified
Type of assay:
other: genetic toxicity in vivo

Test material

Constituent 1
Chemical structure
Reference substance name:
1,2,2,6,6-pentamethylpiperidin-4-ol
EC Number:
219-292-8
EC Name:
1,2,2,6,6-pentamethylpiperidin-4-ol
Cas Number:
2403-89-6
Molecular formula:
C10H21NO
IUPAC Name:
1,2,2,6,6-pentamethylpiperidin-4-ol

Test animals

Species:
mouse
Strain:
not specified

Results and discussion

Test results
Key result
Sex:
male/female
Genotoxicity:
negative
Toxicity:
not specified

Applicant's summary and conclusion