Registration Dossier
Registration Dossier
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EC number: 219-348-1 | CAS number: 2421-28-5
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
In the key study entitled “Statement on 3,3’,4,4’-Benzophenonetetracarboxylic dianhydride: Hydrolysis as a Function of pH: according to OECD Guideline No. 111 (2004) and Council Regulation (EC) No. 440/2008, Method C.7” performed at DR.U.NOACK-LABORATORIEN Sarstedt, Germany in 2012, a hydrolytic half life, at ambient temperature, of less than 10 minutes was assumed based on the data obtained during a preliminary study.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 10 min
- at the temperature of:
- 40 °C
Additional information
In the preliminary test a solution with a concentration of 10 mg/L of the substance was prepared in HPLC-water and immediately injected 10 times into the analytical system. Due to the fast transformation only the transformation product 3,3,4,4 -Benzophenonetetracarboxylic acid (BTCA) could be detected. After 9 minutes (sample preparation, including chromatographic separation) a transformation rate of already 100% was determined on basis of the BTCA measurements. Due to the fast transformation, no hydroloysis testing on basis of the OECD 111 guideline could be performed. A hydrolytic half life of less than 10 minutes could be assumed at environmentally relevant temperatures.
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