Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
epidemiological data
Type of information:
other: TLV
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: TLV reported by a reputable source, but no finalization or publication of TLV was found

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1975
Report date:
1975

Materials and methods

Study type:
other: TLV
Endpoint addressed:
acute toxicity: inhalation
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No information on data sources
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride
EC Number:
219-348-1
EC Name:
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride
Cas Number:
2421-28-5
Molecular formula:
C17H6O7
IUPAC Name:
5-(1,3-dioxo-1,3-dihydro-2-benzofuran-5-carbonyl)-1,3-dihydro-2-benzofuran-1,3-dione
Test material form:
not specified
Details on test material:
no data

Method

Type of population:
occupational
Ethical approval:
not applicable
Details on study design:
no information

Results and discussion

Results:
The threshold limit value (TLV) for BTDA is 1 mg/m3 as proposed by the American Conference of Governmental Industrial Hygienists (ACGIH) in its notice of intended changes of threshold limit values (TLV) in 1975. There is no verification that this TLV was adopted. This is cited in the above-referenced NIOSH Health Hazard Evaluation/Toxicity Determination.

Applicant's summary and conclusion

Conclusions:
It is reported that the ACGIH in 1975 proposed a threshold limit value (TLV) for BTDA of 1 mg/m3. There is no evidence that this value was ever finalized or adopted.