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Vapour pressure

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Description of key information

negligibly low

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

Testing for this endpoint has been waived in accordance with Regulation (EC) No 1907/2006, Annex VII, column 2. Due to the high melting point the assessment can be based on estimation. Vaporisation is deemed negligible as the vapour pressure will be clearly <10^-10 Pa as Guanidine carbonate is a solid ionic crystal. This limit value may be used if required for calculations.

Measurement at such low levels is technically not feasible and in accordance with REACH regulation (Annex XI, 2.) no study is required.

The submission item may speciate to Guanidine (CAS 113-00-8) in the environment, which is discussed in the section on Environmental fate and pathways. Guanidine has a more significant vapour pressure, which is estimated with a fragment constant method (Lyman 1985) to be 2.2 mm Hg at 25 °C (HSDB 2008 using US EPA 2007. Estimation Program Interface (EPI) Suite. Ver.3.20. February). This value corresponds to 293 Pa (conversion factor 133.3224).

  • HSDB Hazardous Substances Databank (2008). GUANIDINE, CASRN: 113-00-8, Number: 7603. Last Revision Date: 2008-08 -26, Last Review Date: Reviewed by SRP 5/8/2008, Update History: Complete Update on 2008 -08-26, 38 fields added/edited/deleted, Created 20071213
  • Lyman WJ (1985) p. 31 In Environmental Exposure From Chemicals Vol I, Neely WB, Blau GE, eds, Boca Raton, FL, U.S.A.CRC Press
  • US EPA United States Environmental Protection Agency (2007). Estimation Program Interface (EPI) Suite. Ver.3.20. February, 2007. Available from, as of Dec 17, 2007: