2-nitro-p-anisidine

Mode of degradation in actual use

Administrative data

Endpoint:

mode of degradation in actual use

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

4 (not assignable)

Data source

Reference

Reference Type:

review article or handbook

Title:

Handbook of Chemical Property Estimation Methods

Author:

[(1) Atkinson R; (2) Meylan WM, Howard PH; (3) Lyman WJ et al

Year:

2011

Bibliographic source:

Environ Toxicol Chem 7: 435-62 (1988); Chemosphere 26: 2293-99 (1993) ; . Washington, DC: Amer Chem Soc pp. 7-4, 7-5 (1990)

Materials and methods

Test guideline

Qualifier:

no guideline available

Principles of method if other than guideline:

Toxnet database

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

5-nitro-o-anisidine

EC Number:

202-770-5

EC Name:

5-nitro-o-anisidine

Cas Number:

99-59-2

IUPAC Name:

2-methoxy-5-nitroaniline

Applicant's summary and conclusion

Executive summary:

Environmental Abiotic Degradation:

The rate constant for the vapor-phase reaction of 5-nitro-o-anisidine with photochemically-produced hydroxyl radicals has been estimated as 3.3X10-11 cu cm/molecule-sec at 25 deg C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 12 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). 5-Nitro-o-anisidine is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3). Aromatic amines such as aniline have weak absorption bands that extend beyond 290 nm(4), therefore p-anisidine may be susceptible to direct photolysis, but the kinetics of this reaction are unknown. Aniline has been shown to undergo indirect photolysis in natural waters containing humic acids(5), therefore it is expected that p-anisidine may also undergo indirect photolysis in natural water.