Registration Dossier
Registration Dossier
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EC number: 202-547-2 | CAS number: 96-96-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number: BY4415000
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,718,1986
- Reference Type:
- other: Authoritative data base
- Title:
- No information
- Author:
- IFA (GESTIS)
- Year:
- 2 011
- Bibliographic source:
- GESTIS - Substance Database (Information system on hazardous substances of the Berufsgenossenschaften)
- Reference Type:
- review article or handbook
- Title:
- DPIM: MFB000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials):- 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J., Prague, Czechoslovakia.: , Avicenum, 1986, 718.
- Reference Type:
- review article or handbook
- Title:
- M143
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE):- Marhold, J. V. Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku 1972, Prague, Czechoslovakia.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- 2-nitro-p-anisidine
- EC Number:
- 202-547-2
- EC Name:
- 2-nitro-p-anisidine
- Cas Number:
- 96-96-8
- Molecular formula:
- C7H8N2O3
- IUPAC Name:
- 4-methoxy-2-nitroaniline
Constituent 1
Test animals
- Species:
- rat
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 14 100 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 value of the substance is found to be 14100 mg/kg in rats by oral route.
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