Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
96-96-8
Author:
Danish EPA model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Multicase model is used to estimate IGC50 (46h) of tetrahymena pyriformis.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-nitro-p-anisidine
EC Number:
202-547-2
EC Name:
2-nitro-p-anisidine
Cas Number:
96-96-8
Molecular formula:
C7H8N2O3
IUPAC Name:
4-methoxy-2-nitroaniline

Test organisms

Test organisms (species):
Tetrahymena pyriformis

Study design

Test type:
not specified
Water media type:
not specified
Limit test:
yes
Total exposure duration:
46 h

Results and discussion

Effect concentrations
Duration:
46 h
Dose descriptor:
other: IG50
Effect conc.:
49.056 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes