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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

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Link to relevant study record(s)

Description of key information

The test substance was shown to have a potential for binding to Ca channels and to act as an antagonist at the nicotinic acetylcholine receptors in in vitro studies. Lesions to cardiomyocytes were induced when administered intraperitoneally in rats. There is evidence that the test substance does inhibit the action of acetylcholine receptor agonists, however it does itself not evoke antinicotinic effects under normal physiological conditions.

Additional information