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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From Oct 13, 2011 to Nov. 28, 2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
according to OECD and EU principles of GLP
Type of method:
static method
Remarks:
using using a U-tube manometer
Temp.:
20 °C
Vapour pressure:
2.98 mBar
Remarks on result:
other: Mean of runs 1 & 2

Table 1: Full test results (study # 85858)

Temp/°C

Temp/K

P/mbar

**P/Pa

Run 1

20

293.15

3.21

321

32 .9

306.05

7.1

710

41.8

314.95

11.7

1170

52.2

325.35

23.6

2360

61 .9

335.05

35.9

3590

72.1

345.25

55.8

5580

Run 2

*20

293.15

2.75

275

33.3

306.45

6.1

610

40.4

313.55

11 .8

1180

53.8

326.95

23.8

2380

63.1

336.25

38.8

3880

71.8

344.95

59.1

5910

* Determined by extrapolation

**Calculated

Conclusions:
The vapour pressure of MEA-LAS was 2.98 mbar at 20°C (mean of runs 1 & 2) (determined by static method using a U-tube manometer; EU Method A.4 (Vapour Pressure))
Executive summary:

The vapour pressure of MEA-LAS was determined by following the EU Method A.4 (Vapour Pressure).

The test was conducted to determine the vapour pressure of a test substance by the Static method - using a U-tube manometer.The static method

involves placing a sample in a bulb maintained at constant temperature and connected to a pressure monitor and a vacuum pump.

The vapour pressure of MEA-LAS was 2.98 mbar at 20°C (mean of runs 1 & 2).

This vapour pressure test is classified as acceptable, and satisfies the guideline requirements of the EU Method A.4 (Vapour Pressure))

Description of key information

The vapour pressure of MEA-LAS was determined following EU Method A.4 (Vapour Pressure).

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of MEA-LAS was 2.98 mbar (298 Pa) at 20°C.

As described in the read across justification documents, the driver of toxicity for human health and environmental endpoints is the LAS moiety of MEA-LAS. Therefore, for risk assessment purposes, the vapour pressure of LAS (3.0E-13 Pa) was used.

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