Glycerides, C16-22

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Not available

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was conducted according to standard guidelines in compliance with GLP

Justification for data waiving:

other:

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

, March 23, 2006

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

, EC no. 761/2009, August 24, 2009

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Remarks:

(Isothermal thermogravimetric effusion method)

Test material

Test material information

Constituent 1

Reference substance name:

Glycerides, C16-22

EC Number:

268-083-8

EC Name:

Glycerides, C16-22

Cas Number:

68002-70-0

Molecular formula:

Triglyceride containing a glycerol backbone esterified to fatty acids with a chain length varying from C16 to C22

IUPAC Name:

Tri (C16-22 fatty acyl) glycerol

Details on test material:

- Name of test material (as cited in study report): Fully hydrogenated high erucic acid rapeseed oil (CAS N° 84681-71-0, EC N° 283-532-8); under the SDA nomenclature, the name of this substance is ‘Glycerides, C16-22’
- Physical state: Solid (white-yellow)
- Analytical purity: 100%
- Expiration date of the lot/batch: December 31, 2010
- Storage condition of test material: At room temperature in the dark

Results and discussion

Vapour pressure

Temp.:

ca. 20 °C

Vapour pressure:

< 0 Pa

Remarks on result:

other: Equivalent to < 1.00 X 10-10 mm Hg at 20°C

Any other information on results incl. tables

The logarithm of the evaporation rate of the reference control substance at 20°C deviated < 10% from the average value obtained during the validation test. This show the acceptability of the data of the reference substances for the determination of the vapour pressure of the test substance.

The equation of reference regression curve was found to be log P₂₀= 1.07 X log V₂₀+ 4.52 (r =0.996, n=10).

The weight loss of the test substance from 210°C to 240°C was lower than the weight loss of benzo(ghi)perylene (reference substance with lowest vapour pressure) at the same temperatures. From this, it was concluded that the vapour pressure of the test substance at 20°C is < 1.33 x 10^-8Pa or < 1.00 X 10^-10mm Hg (the vapour pressure of benzo(ghi)perylene).

Applicant's summary and conclusion

Conclusions:

Under the test conditions, the vapour pressure of fully hydrogenated high erucic acid rapeseed oil was found to be < 1.33 x 10-8 Pa =< 1.00 x 10-10 mm Hg at 20°C.

Executive summary:

A study was conducted to determine the vapour pressure of fully hydrogenated high erucic acid rapeseed oil according to isothermal thermogravimetric effusion method (OECD Guideline 104 and EU method A.4).

7.51 - 9.44 mg of the test substance applied on glass plate and placed in the thermogravimetric analyzer. The weight loss of the test substance measured continuously as a function of time from 100°C to 240°C. Benzo(ghi)perylene, chrysene, hexachlorobenzene, naphthalene and water were used as reference substances for validation.

The weight loss of the test substance was lower than the weight loss of benzo(ghi)perylene (reference substance with lowest vapour pressure) at the same temperatures. From this, it was concluded that the vapour pressure of the test substance at 20°C is < 1.33 x 10^-8Pa or < 1.00 X 10^-10mm Hg (the vapour pressure of benzo(ghi)perylene).

Under the test conditions, the vapour pressure of fully hydrogenated high erucic acid rapeseed oil was found to be < 1.33 x 10^-8Pa =< 1.00 x 10^-10mm Hg at 20°C.