Registration Dossier
Registration Dossier
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EC number: 484-470-6 | CAS number: 623-40-5
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.088 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.88 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.009 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 2 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.501 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.05 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.049 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Environmental fate and pathways
Biodegradation: Not readily biodegradable (9% in 28 d, OECD 301 B)
Bioaccumulation: No potential for bioaccumulation; log Pow = 1.43 (22 °C, pH 7, OECD 117)
Aquatic short-term toxicity
Fish: LC50 (96 h) > 100 mg/L (nominal, OECD 203, O. mykiss)
Aquatic invertebrates: EC50 (48 h) > 100 mg/L (nominal, OECD 202, D. magna)
Algae: ErC50 (72 h) = 88 mg/L (nominal, OECD 201, P. subcapitata)
Aquatic long-term toxicity
Fish: no data available
Aquatic invertebrates: no data available
Algae: NOErC (72 h) = 32 mg/L (nominal, OECD 201, P. subcapitata)
Conclusion on CLP
2-Pentanone oxime (CAS 623-40-5) is not rapidly biodegradable, the substance has a low potential for bioaccumulation (log Pow: 1.43). The lowest acute aquatic toxicity ErC50 (72 h) is 88 mg/L (NOErC (72 h): 32 mg/L). Based on the determined acute effect concentration of ErC50 (72 h): 88 mg/L and the lack of rapid degradability the substance needs to be classified aquatic chronic 3 according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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