Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Individual study

Data source

Reference
Reference Type:
publication
Title:
Bronchial asthma and asthmatic bronchitis in the chemical industry
Author:
Lerner R
Year:
1955
Bibliographic source:
Industrial Medicine and Surgery, 24(10), 454-458

Materials and methods

Study type:
other: survey
Endpoint addressed:
respiratory sensitisation
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Survey of health effects in exposed workers.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Phosphoryl trichloride
EC Number:
233-046-7
EC Name:
Phosphoryl trichloride
Cas Number:
10025-87-3
Molecular formula:
Cl3OP
IUPAC Name:
phosphoroyl trichloride

Results and discussion

Clinical signs:
Phosphoryl trichloride is a potential cause of occupational asthma.
Results of examinations:
Phosphoryl trichloride as a potential cause of occupational asthma.
Outcome of incidence:
No data

Applicant's summary and conclusion

Executive summary:

The author mentions phosphoryl trichloride as a potential cause of occupational asthma.