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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary citation in handbook, original reference not available

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Patty's industrial hygiene and toxicology: 2.5.4 Dicumyl peroxide
Author:
Clayton GD, Clayton FE
Year:
1993
Bibliographic source:
572-573, Wiley-Interscience, John Wiley & Sons, New York, NY
Reference Type:
secondary source
Title:
Bulletin T-104, Revision I
Author:
Hercules Rubber Chemicals, Hercules Powder Company
Year:
1964
Bibliographic source:
internal report, not available

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
Patch test
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Type of population:
not specified
Controls:
No data
Route of administration:
dermal

Results and discussion

Results of examinations:
Slight skin irritation, but no skin sensitisation were reported in 200 human volunteers patch tested with technical grade of 90 % dicumyl peroxide.

Applicant's summary and conclusion