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EC number: 215-481-4 | CAS number: 1327-53-3
With water formulation, 0.93 ± 1.1 % of the applied dose accumulated in the receptor fluid and 0.98 ± 0.96% was in skin after surface wash. The soap and water wash accounted for 69.8 ± 16.4%. If in vitro percutaneous absorption is calculated as receptor fluid accumulation plus residual skin concentration (after soap and water wash) then the absorption in human skin is 1.9% from water. It appears from the text of the publication that these detailed results are for the low dose (0.000024 µg/cm2) application only.
However, in the discussion section of the publication, it is mentioned that for the high dose (2.1 µg/cm2), the absorption/penetration was 0.04 µg/cm2, that is also around 2%.
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