Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Diarsenic trioxide is classified as Skin Corr 1B, according to Regulation (EC) No 1272/2008 (harmonised classification) based on data reviewed and discussed by the EU technical committee on classification and labelling. The corresponding hazard statement is H314: Causes severe skin burns and eye damage, since severe adverse effects on the eyes are also to be expected for substances that are known corrosives to skin.

Key value for chemical safety assessment

Skin irritation / corrosion

Link to relevant study records
Reference
Endpoint:
skin corrosion: in vitro / ex vivo
Data waiving:
other justification
Justification for data waiving:
other:
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation: in vitro / ex vivo
Data waiving:
other justification
Justification for data waiving:
other:
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irreversible damage)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Diarsenic trioxide is classified as Skin Corr 1B - H314 (Causes severe skin burns and eye damage), according to Regulation (EC) No 1272/2008 based on data reviewed and discussed by the EU technical committee on classification and labelling.

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