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Short-term toxicity to aquatic invertebrates

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Description of key information

48h EC50 (Daphnia magna, mobility) = 2.8 mg/L (nominal concentration, OECD 202) 

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2.8 mg/L

Additional information

Three reliable short term studies with invertebrates are available for C12 -18AS Na (CAS 68955-19-1). A key GLP study by Marshall (1993) was performed according to OECD 202 guideline. A static test was performed with six different concentrations in the range 0-10 mg a.i./L with Daphnia magna. The test resulted in the 48-h EC50 value of 2.8 mg a.i./L (nominal concentrations in agreement with the measured ones). In a supporting GLP study (Scholz 1997) Daphnia magna was exposed to six different concentrations of C12-18AS Na (CAS 68955-19-1) in the range 1 -100 mg/L. A static system according to the EG Method C2 was performed. The 48-h EC50 value was 15 mg a.i./L (nominal concentrations in agreement with the measured ones). Finally, the third non-GLP supporting study by Kamp (1992) was performed according to DIN 38412 (11) test method. Daphnia magna was exposed in a static system to six concentrations of the test substance in the range 0-128 mg/L. The 48-h EC50 value was 12 mg/L (nominal).