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Toxicity to microorganisms

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Description of key information

With the exception of Pseudomonas putida (16 h TT (EC3)>50 mg/L) cumene hydroperoxide shows a high toxicity to microorganisms in cell multiplication inhibition tests (Entosiphon sulcatum Stein: 72 h-TT (EC5)=8.5 mg/L; Chilomonas paramaecium: 48 h TT (EC5)=0.91 mg/L and Uronema parduczi: 20 h TT (EC5)=0.35 mg/L nominal each).

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
50 mg/L

Additional information

Pseudomonas putida was exposed for 16 h to cumene hydroperoxide under static conditions. In the cell multiplication inhibition test, a TT (EC3)>50 mg/L nominal was obtained. In a cell multiplication inhibition test using Entosiphon sulcatum Stein, Chilomonas paramaecium, and Uronema parduczi as test organisms, a 72 h-TT (EC5)=8.5 mg/L (Entosiphon s.), a 48 h TT (EC5)=0.91 mg/L (Chilomonas p.), and a 20 h TT (EC5)=0.35 mg/L (Uronema p.; nominal Each) were determined.