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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

If inhaled:

Remove to fresh air.

If not breathing, give artificial respiration.

If breathing is difficult, give oxygen.

Get immediate medical advice/ attention.

In case of skin contact:

Wash off immediately with plenty of water for at least 15 minutes.

Get medical advice/ attention.

Take off contaminated clothing and shoes immediately.

Wash contaminated clothing before reuse.

In case of eye contact:

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Remove contact lenses, if present and easy to do. Continue rinsing.

If eye irritation persists: Get medical advice/ attention.

If swallowed:

Clean mouth with water and drink afterwards plenty of water.

Do not induce vomiting without medical advice.

Call a physician or poison control center immediately.

Most important symptoms and effects, both acute and delayed


Causes eye irritation.



Abdominal pain

Liver disorders

More severe effects if alcohol is consumed.


Indication of any immediate medical attention and special treatment needed:

Treat symptomatically.

Fire-fighting measures

Suitable extinguishing media:

Use water spray to extinguish.

Carbon dioxide (CO2)

Dry chemical

Alcohol-resistant foam

Unsuitable extinguishing media:

High volume water jet

Specific hazards during fire fighting:

Thermal decomposition can lead to release of irritating gases and vapours.

The product will float on water and can be reignited on surface water.

Hazardous combustion products:

Nitrogen oxides (NOx)

Special protective equipment for fire-fighters:

Wear self-contained breathing apparatus and protective suit.

Further information:

Use a water spray to cool fully closed containers.

Do not allow run-off from fire fighting to enter drains or water courses.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

Wear appropriate personal protective equipment.

Local authorities should be advised if significant spillages cannot be contained

Environmental precautions:

Avoid release to the environment.

Do not flush into surface water or sanitary sewer system.

Methods and materials for containment and cleaning up:

Contain spillage, soak up with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and transfer to a container for disposal according to local / national regulations.

After cleaning, flush away traces with water.

Eliminate all ignition sources if safe to do so.

Handling and storage

Precautions for safe handling:

Do not breathe vapors or spray mist.

Do not get on skin or clothing.

Do not get in eyes.

Avoid contact with skin, eyes and clothing.

Do not swallow.

Use only with adequate ventilation.

Wash thoroughly after handling.

Keep away from fire (No Smoking).

Keep away from fire, sparks and heated surfaces.

Do not use sparking tools.

Conditions for safe storage, including any incompatibilities:

Keep containers tightly closed in a dry, cool and well-ventilated place.

Advice on protection against fire and explosion:

Keep product and empty container away from heat and sources of ignition.

Hygiene measures:

Handle in accordance with good industrial hygiene and safety practice

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
UN 2265
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Inland waterway transport (UN RTDG/ADN(R))

UN number:
UN 2265
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Marine transport (UN RTDG/IMDG)

UN number:
UN 2265
Shipping information
Proper shipping name and description:
Chemical name:
N,N - Dimethylformamide
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Air transport (UN RTDG/ICAO/IATA)

UN number:
UN 2265
Shipping information
Proper shipping name and description:
Chemical name:
3 - Flammable Liquids
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Exposure controls / personal protection

Engineering measures

Good general ventilation (typically 10 air changes per hour) should be used. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits. If exposure limits have not been established, maintain airborne levels to an acceptable level.

Personal protective equipment

Eye protection:

Safety glasses with side-shields



Hand protection:

Rubber gloves, Neoprene gloves. The data about break through time/strength of material are standard values! The exact break through time/strength of material has to be obtained from the producer of the protective glove.

Skin and body protection:

Wear suitable protective clothing.

Respiratory protection:

Use respiratory protection unless adequate local exhaust ventilation is provided or exposure assessment demonstrates that exposures are within recommended exposure guidelines.

Protective measures:

Remove respiratory and skin/eye protection only after vapors have been cleared from the area.

Ensure that eye flushing systems and safety showers are located close to the working place.

Use personal protective equipment as required.

Stability and reactivity


Stable under recommended storage conditions.

Chemical stability:

Stable under normal conditions.

Possibility of hazardous reactions: Heating can release hazardous gases., Hazardous polymeri-zation does not occur.

Conditions to Avoid

Keep away from sources of ignition - No smoking.

Take precautionary measures against static discharges.

Heat, flames and sparks.

Materials to avoid:

Strong oxidizing agents

Strong acids

Halogenated compounds

Hazardous Decomposition Products

• Heating or fire can release toxic gas (Nitrogen oxides (NOx) Carbon dioxide (CO2) Carbon monoxide Ammonia)

Disposal considerations

Waste Disposal Method

In accordance with local and national regulations.

Waste must be classified and labelled prior to recycling or disposal.

Contaminated Packaging

Empty containers should be taken to an approved waste han-dling site for recycling or disposal.