Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In an LLNA study conducted according to OECD 429, female CBA/Ca mice (five/group) received 0.5%, 5%, or 50% (v/v) test substance diluted using 4:1 acetone:olive oil (AOO). Lymph node stimulation indices of less than three (3) were measured for the three test groups relative to AOO vehilce mice. The test substance was considered to be a non-sensitizer under the conditions of the test.

Migrated from Short description of key information:

Non-sensitiser according to a mouse LLNA study (OECD 429).

Justification for classification or non-classification

The findings of the testing do not warrant classification for skin sensitisation.