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Diss Factsheets
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EC number: 203-632-7 | CAS number: 108-95-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of dehydrogenase activity and the inhibition of microbial nitrification were tested in the presence of phenol at concentrations of 1, 10, 100, 1000 mg/kg soil dry weight. As the applied enzymatic activities are used for the assessment of pesticides, it is assumed that the standarized method for the testing for pesticides was applied. In contrast to the standardized method, the incubation period was 14 days (guideline: at least 28 days). Lowest endpoint was the EC10 for dehydrogenase activity (100 mg/kg soil dry weight).
Key value for chemical safety assessment
- Long-term EC10 or NOEC for soil microorganisms:
- 100 mg/kg soil dw
Additional information
The data on effects of phenol on terrestrial soil organisms is presented in EU RAR (2006) in Section 3.2.3 (Terrestrial compartment, page 44ff).
It is stated that the most sensitive endpoint for soil microorganisms is the NOEC > 100 mg/kg dry weight obtained for reduction of hydrogenase activity (content of organic matter not stated; Maas & Auspurg, 1984).
The inhibition of dehydrogenase activity and the inhibition of microbial nitrification were tested in the presence of phenol at concentrations of 1, 10, 100, 1000 mg/kg soil dry weight. The applied soil and further test conditions are not described. At the same time several pesticides were tested. As the applied enzymatic activities are used for the assessment of pesticides, it is assumed that the standardized method for the testing for pesticides was applied. In contrast to the standardized method, the incubation period was 14 days (guideline: at least 28 days).
Based on the percentual deviation of dehydrogenase activity from the untreated control samples, it can be estimated that the EC10 for dehydrogenase activity is 100 mg/kg soil dry weight. Based on the nitrogen concentrations, shown in a diagram, it can be concluded that the EC50 for nitrification is in the range of 100 - 1000 mg/kg soil dry weight.
As it is assumed that the standard test for the testing of chemicals and pesticides were used and as it is not expected that further tests will result in completely different results, no further tests are considered to be necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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