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Administrative data

Description of key information

Flue Dust is not acutely toxic.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
6 040 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

To save animal life, no separate acute oral toxicity testing was done. Information are available from a oral repeated dose toxicity study, where flue dust was tested as part of the animal diet. Even with the highest tested dose (1848 mg/kg bw in the dose range find study) no mortality was observed. So it is assumed that in a single acute toxicity test, even a dose of 2000 mg/kg bw will not implicate mortality.

In an acute dermal toxicity study in rats with Flue Dust, no deaths occured at the limit dose of 2000 mg/kg bw. Therefore, the LD50 for acute dermal toxicity is > 2000 mg/kg bw.

From an acute inhalation toxicity study in rats with Flue Dust, it was concluded that the 4-hour LC50 for Flue Dust is above 6.04 g/m³ for male and female rats.

Justification for classification or non-classification

The available information indicates that Flue Dust is not acutely toxic. Therefore, classification for acute toxicity is not warranted.