Calcium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate

Endpoint summary

Description of key information

The toxicity to aquatic organisms is assessed based on a category approach. The category members are composed of a structurally analogue organic part but different metals that are laked with the organic structure. At environmentally relevant pH values disintegration of the molucule and a release of the metal component is not expected. Therefore an influence of the laked metal part is not expected. Aquatic algae toxicity data are available for different members of the category. Below a full listing of available aquatic toxicity data is given:

Table: overview of aquatic toxicity data available for the category:

Study	Guideline / GLP	Species	Endpoint	Effect value	Category member	Remark
Fish short-term toxicity	OECD 203 / GLP	Danio rerio	96-h LC50	> LoWs	CAS No 7585-41-3	At a loading rate of 100 mg/L
	OECD 203 / GLP	Danio rerio	96-h LC50	> LoWs	CAS No 7023-61-2	At a loading rate of 100 mg/L
Daphnia short-term toxicity	OECD 202 / non-GLP	Daphnia magna	48-h EC50	> LoWs	CAS No 5281-04-9	At a loading rate of 100 mg/L
	OECD 202 / GLP	Daphnia magna	48-h EC50	> LoWs	CAS 73612-29-0	At a loading rate of 1 mg/L
	OECD 202 / GLP	Daphnia magna	48-h EC50	> LoWs	CAS 7585-41-3	At a loading rate of 100 mg/L
	OECD 202 / GLP	Daphnia magna	48-h EC50	> LoWs	CAS 7023-61-2	At a loading rate of 100 mg/L
	OECD 202 / GLP	Daphnia magna	48-h EC50	> LoWs	CAS 5280-66-0	At a loading rate of 100 mg/L
Alga toxicity	OECD 201 / GLP	Pseudokirchneriella subcapitata	72-h ErC50 72-h NOEC	> LoWs > LoWs	CAS 73612-29-0	At a loading rate of 2 mg/L
	OECD 201 / GLP	Pseudokirchneriella subcapitata	72-h ErC50 72-h ErC10	> LoWs > LoWs	CAS 7023-61-2	At a loading rate of 100 mg/L
Microorganisms toxicity	OECD 209 / GLP	Activated sludge (domestic)	30-min (EC20) NOEC	≥1000 mg/L	CAS 7585-41-3
	OECD 209 / GLP	Activated sludge (domestic)	3-h (EC15) NOEC	≥100 mg/L	CAS 7023-61-2

LoWs: Limit of water solubility