Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-276-6 | CAS number: 611-71-2
Endpoint summary
Administrative data
Description of key information
LD50 (oral,rat): ca. 5000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
In an acute toxicity study (similar to OECD 401) conducted by BASF AG (1987) groups of 10 rats were administered doses of 1470, 3160 and 5000 mg/kg bw by gavage and observed for 14 days for lethality and clinical signs of intoxication. The mortality rate was 0/10, 1/10 and 5/10 in the low, mid and high dose groups, respectively. Clinical symptoms at 3160 mg/kg bw was dyspnea, apathy, staggering, red-brown urine, piloerection and poor general state; these symptoms were observed until day 2 or 3. At 5000 mg/kg bw dyspnea, apathy, staggering, tremors, red-brown urine, piloerection and poor general state; these symptoms were observed until 5 hours after dosing (tremors) or even until day 1, 2 or 3. The LD50 was found to be approx. 5000 mg/kg bw.
Justification for selection of acute toxicity – oral endpoint
only available study
Justification for classification or non-classification
No need for classification according to the EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
