Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Skin: not irritating
Eye irritation: serious eye damage

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Skin irritation

No skin reaction was noted at any reading 1, 24, 48, or 82 h after semiocclusive dermal exposure to 0.5 g of the test substance (80% aqueous formulation) for 4 h in any of 3 White Vienna rabbits (BASF 1987).

Eye irritation

In three White Vienna rabbits the instillation of 0.1 mL of the test substance (80% aqueous formulation into the conjunctival sac of one eye caused reddening (grade 2) and slight to well-defined swelling (grade 1-2) 1 & 24 hours after application (no washing). There were severe effects noted on cornea and iris. The test substance showed a risk of serious eye damage (BASF 1987).

Justification for selection of skin irritation / corrosion endpoint:
Only available study

Justification for selection of eye irritation endpoint:
Only available study

Effects on eye irritation: highly irritating

Justification for classification or non-classification

Based on the available studies data on skin and eye irritating properties the test item would have to be classified as not irritating to skin but as eye irritant Cat. 1 (H318) according to the EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No 1272/2008.