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Toxicity to aquatic algae and cyanobacteria

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Description of key information

The Desmodesmus subspicatus  were exposed to  3-((9,10-Dihydro-9,10-dioxo-4-(methylamino)-1-anthracenyl)amino)-N,N-dimethyl-n-propyl-1-Propanaminium-bromid (Bluequat bromid), The Measured concentrations were >80% of nominalThe 72h For Nominal, EyC50 value  was 12.2mg a.i /L with 95% CL of  11.3 - 13.2mg/L and For Geometric Mean Measured EyC50 value  was 11.6mg a.i /L with 95% CL of  10.7 - 12.3mg/L  and The 72h For Nominal, ErC50 value  was 20.7mg a.i /L with 95% CL of  20.0 -21.3mg/L and For Geometric Mean Measured ErC50 value  was 20.3mg a.i /L with 95% CL of  20.0 - 20.7mg/L

Key value for chemical safety assessment

Additional information

In a 72 -hour acute toxicity study, the cultures of Desmodesmus subspicatus were exposed to 3-((9,10-Dihydro-9,10-dioxo-4-(methylamino)-1-anthracenyl)amino)-N,N-dimethyl-n-propyl-1-Propanaminium-bromid (Bluequat bromid), The Measured concentrations were >80% of nominal, Hence, The nominal concentrations of Control, 1, 3, 9, 27 and 81mg a.i./L, under static conditions in accordance with OECD guideline 201, The EyC50 value were based on biomass for nominal was 12.2mg a.i /L with 95% CL of 11.3 - 13.2mg/L and For Geometric Mean Measured EyC50 value was 11.6mg a.i /L with 95% CL of 10.7 - 12.3mg/L and , The ErC50 value were based on growth rate for nominal was 20.7mg a.i /L with 95% CL of 20.0 -21.3mg/L and For Geometric Mean Measured ErC50 value was 20.3mg a.i /L with 95% CL of 20.0 - 20.7mg/L

There were no compound related phytotoxic effects.

This toxicity study is classified as acceptable and satisfies the guideline requirements for the OECD 201 fershwater alga and cyanobacteria toxicity study

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