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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
not specified
GLP compliance:
yes
Analytical monitoring:
no
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
Number of fish:
control: 7
test: 7
Test type:
not specified
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h
Post exposure observation period:
No mortalities noted.
Hardness:
None
Test temperature:
None
pH:
Control medium:
At start: 7.9 At End: 8.4
Test (1000 mg/l):
At start: 8.0 At end: 8.2
Dissolved oxygen:
Control medium:
At start: 98 %; at end: 97 %
Test (1000 mg/l):
At start: 99 %; at end: 97 %
Salinity:
None
Nominal and measured concentrations:
None
Details on test conditions:
None
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/L
Conc. based on:
test mat.
Details on results:
None
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Sublethal observations / clinical signs:

None

Validity criteria fulfilled:
yes
Conclusions:
LC0: 1000 mg/L
LC50: >1000 mg/L
Executive summary:

The acute fish toxicity test was performed according to equivalent or similar guideline as OECD 203. Rainbow trout were used in this test.


In conclusion:


LD0 =1000 mg/L


LD50 ≥1000 mg/L

Description of key information

Three studies investigating the short term toxicity to fish are available. In the key study, test was performed according to OECD Guideline 203.


Rainbow trout were used in this test. The LC50 after 96 hours was determined to be >1000 mg/l.


In other supporting studies in which no guideline was followed, the TL50 was again found to be >1000 mg/l.


Oncorhynchus mykiss were exposed to the substance for 48 hours at these following different concentrations: 100, 200 and 1000 mg/L

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information