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Environmental fate & pathways

Additional information on environmental fate and behaviour

Administrative data

Endpoint:
additional information on environmental fate and behaviour
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March to December 1978
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The study is well-characterized in the report; however, it was not conducted according to modern guidelines.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1978

Materials and methods

Principles of method if other than guideline:
14C-TBPA applied to silica gel and irradiated with UV light for varying lengths of time. Analyzed via TLC, GC, Liquid scintillation.
GLP compliance:
not specified
Type of study / information:
Hydrolysis and UV degradation.

Test material

Constituent 1
Reference substance name:
14C-tetrabromophthalic anhydride
IUPAC Name:
14C-tetrabromophthalic anhydride
Details on test material:
14C-TBPA; see rat PK study.

Results and discussion

Any other information on results incl. tables

Test article rapidly hydrozyed on silica gel to TBPA acid in the absence of light. ID as the TBPA-acid confirmed by GC using authentic standard.

On UV radiation, test article rapidly and steadily degraded to other products. Half life estimated as ~ 5hr, degradation rate followed first order kinetics during the first few hrs and second order kinetics for the remaining experimental time. Ten degradants detected by TLC. Maximum amounts reached at 1 -2 days of irradiation and then gradually decreased to yield more polar products. The later was suspected of being polymerized product due to TLC behaviour (Maximum of 39% of applied 14C-activity after 2 days irradiation). Amount of other 14C-materials ranged from 0 -7% of applied radioactivity. Total 14C-material (recovery) decreased with time (96.93% at t0 to 31.56% at d10) indicating formation of volatile degradation products, which were not characterized.

Applicant's summary and conclusion

Conclusions:
14C-TBPA applied to silica gel and irradiated with UV light. 14C-TBPA rapidly hydrolyzed in the absence of light to TBPA-acid. Further degradation occurred with exposure to light. The half life was estimated as ~5 hr.
Executive summary:

14C-TBPA applied to silica gel and irradiated with UV light. 14C-TBPA rapidly hydrolyzed in the absence of light to TBPA-acid. Further degradation occurred with exposure to light. The half life was estimated as ~5 hr.