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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Principles of method if other than guideline:
No information available
GLP compliance:
no
Remarks:
pre-GLP
Test type:
other: No information available

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction products of 6-hydroxy-5-nitrosonaphthalene-2-sulfonic acid, chelated with iron (3+), sodium salts.
EC Number:
943-973-5
Molecular formula:
not available being an UVCB substance
IUPAC Name:
Reaction products of 6-hydroxy-5-nitrosonaphthalene-2-sulfonic acid, chelated with iron (3+), sodium salts.

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
water
Details on oral exposure:
VEHICLE
- Concentration in vehicle: 10 - 50 %.


Control animals:
not specified
Details on study design:
- Duration of observation period following administration: 14 days.

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 8 200 mg/kg bw
Based on:
test mat.
Other findings:
Dyspnea, apathy, prone position, agressiveness, tumbling, slowed movements, diarrhea, feces urine stained green, general condition was bad, organs and connective tissue were stained.

Applicant's summary and conclusion

Interpretation of results:
other: not classified as harmful/toxic according to the CLP Regulation (EC) No.1272/2008
Conclusions:
LD50=. 8200 mg/kg b.w.
Executive summary:

Method

The acute oral toxicity of the substance was evaluated after the exposure of rats to 10 -50 % acqueous suspensions of the substance. The animals were observed for 14 days after the administration of the substance.

Observations:

During the test the following findings were observed: dyspnea, apathy, prone position, agressiveness, tumbling, slowed movements, diarrhea, feces urine stained green, general condition was bad, organs and connective tissue were stained.

Results:

The LD50 was found to be ca. 8200 mg/kg b.w.