Registration Dossier
Registration Dossier
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EC number: 202-941-4 | CAS number: 101-42-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- The growth of Colpidium campylum has been determined in a 43 h test and the minimal active dose was determined.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- yes
- Remarks:
- Final concentration 0.25 mL acetone/ 50 mL test solution
- Test organisms (species):
- Colpidium campylum
- Test type:
- static
- Water media type:
- not specified
- Total exposure duration:
- 43 h
- Test temperature:
- 20°C
- Details on test conditions:
- TEST SYSTEM
- Fill volume: 50 mL
- No. of vessels per concentration (replicates): 5
- No. of vessels per vehicle control (replicates): 5
Further information is depicted in the illustration below. - Duration:
- 43 h
- Dose descriptor:
- LOEC
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Details on results:
- At the highest concentration tested (10 mg/L), no inhibition of the growth of Colpidium campylum was observed when compared to the solvent control.
- Reported statistics and error estimates:
- covariance analysis
- Conclusions:
- 43 h- LOEC Colpidium campylum: > 10 mg/L (highest tested concentration)
- Executive summary:
At the highest concentration tested (10 mg fenuron /L), no inhibition of the growth of Colpidium campylum was observed when compared to the solvent control.
Even if Colpidium campylum is not a standard test organisms, the result is considered to be relevant for the risk assessment of fenuron since the test was performed as reproduction test.
According to Granner and Foissner (1989) this species was also found in sewage treatment plants and is hence relevant.
Bruno Ganner und Wilhelm Foissner:Taxonomy and ecology of some ciliates (Protozoa, Ciliophora) of the saprobic system. III. Revision of the genera Colpidium and Dexiostoma, and establishment of a new genus, Paracolpidium nov. gen.Hydrobiologia, Volume 182, Number 3, S. 181–218, Verlag Springer Netherlands, September 1989
Reference
Description of key information
43 h- LOEC Colpidium campylum: > 10 mg/L (highest tested concentration)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 10 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
