1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactose

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)

GLP compliance:

not specified

Type of method:

flask method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

ca. -0.51

Temp.:

20 °C

Remarks on result:

other: pH was not measured

Details on results:

Results for the octanol-water partition coefficients of sucralose are: Measured log Pow = -0.51 +/- 0.03

Conclusions:

The log Pow of Sucralose was measured in accordance to the EPA "Shake Flask" method (EPA Test Guidelines "Partition Coefficient (n-Octanol/Water), Estimitation by Liquid Chromatography" OPPTS 830.7570, EPA 712-C-96-040, August 1996) .The measured log Pow of Sucralose is -0.51 +/- 0.03.

Description of key information

The log Pow of Sucralose was measured in accordance to the EPA "Shake Flask" method (EPA Test Guidelines "Partition Coefficient (n-Octanol/Water), Estimitation by Liquid Chromatography" OPPTS 830.7570, EPA 712-C-96-040, August 1996). The measured log Pow of Sucralose is -0.51 +/- 0.03.

Key value for chemical safety assessment

Log Kow (Log Pow):

-0.51

at the temperature of:

20 °C