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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
GLP compliance:
not specified
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
ca. -0.51
Temp.:
20 °C
Remarks on result:
other: pH was not measured
Details on results:
Results for the octanol-water partition coefficients of sucralose are: Measured log Pow = -0.51 +/- 0.03
Conclusions:
The log Pow of Sucralose was measured in accordance to the EPA "Shake Flask" method (EPA Test Guidelines "Partition Coefficient (n-Octanol/Water), Estimitation by Liquid Chromatography" OPPTS 830.7570, EPA 712-C-96-040, August 1996) .The measured log Pow of Sucralose is -0.51 +/- 0.03.

Description of key information

The log Pow of Sucralose was measured in accordance to the EPA "Shake Flask" method (EPA Test Guidelines "Partition Coefficient (n-Octanol/Water), Estimitation by Liquid Chromatography" OPPTS 830.7570, EPA 712-C-96-040, August 1996). The measured log Pow of Sucralose is -0.51 +/- 0.03.

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.51
at the temperature of:
20 °C

Additional information