Registration Dossier
Registration Dossier
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EC number: 292-146-9 | CAS number: 90552-24-2
Endpoint summary
Administrative data
Description of key information
2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) (CAS 90552-24-2 / EC 292-146-9) was determined to be poorly soluble in water.
In accordance with Annexes VII and VIII of REACH, Column 2, aquatic toxicity is unlikely to occur due to the water solubility of the substance.
Therefore, short-term toxicity testing to aquatic species were waived and a long-term Daphnia Reproduction Test in accordance with the OECD Testing Guideline 211 was performed (Annex IX of REACH).This study showed that the test item 2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) (CAS 90552-24-2) had no effects on parental immobilization, reproduction and body length at the highest attainable test concentration (0.14 mg/L) under experimental conditions.
No Observed Effect Concentration (NOEC) was determined to be 0.14 mg/L based on reproduction, immobilisation and body length.
Toxicity control conducted during the ready biodegradability study conducted in accordance with the OECD Testing Guideline 301F showed that the presence of 2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) did not impact on the degradation of the reference substance, thus indicating that it was not toxic to aquatic microorganisms from the inoculum.
An assessment was conducted to evaluate the long-term toxicity to fish of 2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) based on physicochemical properties and available data on the substance.
As a result of this assessment and in accordance with Annex IX of REACH and ECHA (2016), it is concluded that there are no grounds for concern for the aquatic compartment given the physico chemical properties and the available aquatic toxicity data for the substance. In addition, it is clear from the exposure assessment for the substance that the predicted exposure concentrations for fresh and marine water compartments, for all uses in the EU were 0 mg/L and as such, vertebrate testing to establish the long-term toxicity of 2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) to fish would be unjustified.
Additional information
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