Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance does not meet the criteria for classification as acute toxicity or STOT SE by the oral route and no systemic effects have been observed in in vivo studies with dermal exposure (e.g. skin irritation, skin sensitisation)
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
In accordance with Annex VIII of REACH, Column 2, testing by the dermal route does not need to be conducted since the substance does not meet the criteria for classification as acute toxicity or STOT SE by the oral route and the physiological properties of the substance suggest that it does not a potential for a significant rate of absorption through the skin (see Section 7.1).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion