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Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08 June - 15 Sept, 1994
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted followin EU guideline and in accordance with GLP. Study material is well characterized.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
Capillary method
GLP compliance:
yes
Type of method:
other: Metal block method

Test material

Constituent 1
Chemical structure
Reference substance name:
A mixture of: bis(1S,2S,4S)-(1-benzyl-4-tert-butoxycarboxamido-2-hydroxy-5-phenyl)pentylammonium succinate; isopropyl alcohol
EC Number:
414-810-0
EC Name:
A mixture of: bis(1S,2S,4S)-(1-benzyl-4-tert-butoxycarboxamido-2-hydroxy-5-phenyl)pentylammonium succinate; isopropyl alcohol
Cas Number:
144163-85-9
Molecular formula:
Empirical formula: C25H35N2O5
IUPAC Name:
butanedioic acid; propan-2-ol; bis(tert-butyl N-[(4R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate)

Results and discussion

Melting / freezing point
Melting / freezing pt.:
>= 143.5 - <= 145 °C
Atm. press.:
ca. 1 atm
Decomposition:
no
Remarks on result:
other: Sample melts in the range 143.5°C to 145.0°C.

Any other information on results incl. tables

The test material cooled to an off-white clear solid after the test.

Applicant's summary and conclusion

Conclusions:
The melting temperature of A-88820.605 is in the range 143.5°C to 145.0°C.