Quaternary ammonium compounds, N,N,N'-tris(hydroxyethyl)-N,N'-dimethyl-N'-C16-18 (even numbered) and C18 unsatd., alkyltrimethylenedi-, bis(Me sulfates) (salts)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From October 27, 2016 to July 03, 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: OECD 115

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: UNE 55-50

Deviations:

no

GLP compliance:

not specified

Type of method:

other: Tensiometer Kruss Standard plate method

Key result

Water solubility:

4.8 mg/L

Conc. based on:

test mat.

Temp.:

25 °C

Remarks on result:

other: Critical micelle concentration

Results: The intercept of the regression lines at stable surface tension and the line representing the lineal decrease of Surface tension is considered to represent the Critical Micelle Concentration (CMC).

The Critical Micelle Concentration is therefore estimated as 4.8 mg/l (refere attached background material for CMC graph).

C (ppm)	ST mN/m	log C
1.16	39.1	0.065
2.21	34.3	0.344
5.1	31.3	0.708
10.37	31.7	1.016
15.5	32.4	1.19
20.48	32.3	1.311
40.99	32.9	1.613

Conclusions:

Under the study conditions, the the CMC or water solubility of the test substance was determined to be 4.8 mg/L at 25°C.

Executive summary:

A study was conducted to determined the water solubility of the test substance, Quaternary ammonium compounds, N,N,N'-tris(hydroxyethyl)-N,N'-dimethyl-N'-tallow alkyltrimethylenedi-, bis(Me sulfates) (salts), based on critical micelle concentration (CMC), according to the OECD Guideline 115 and EU Method A.5. Due to the surface activity of the test substance, the CMC value was considered as a water soluibility equivalent in accordance with the ECHA R.7a Guidance. Under study conditions, the CMC of the test substance was determined to be 4.8 mg/L at 25˚C (Carrillo, 2017).

Description of key information

The water solubility was determined based on critical micelle concentration (a water solubility equivalent of surfactant), according to OECD Guideline 115 and EU Method A.5 (Carrillo, 2017).

Key value for chemical safety assessment

Water solubility:

4.8 mg/L

at the temperature of:

25 °C