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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
See attached background material, attached further below in the present section.
Qualifier:
according to guideline
Guideline:
other: REACH guidance on information requirements and chemical safety assessment, chapter R.6: QSARs and grouping of chemicals, May 2008.
Principles of method if other than guideline:
(Q)SAR calculation
GLP compliance:
no
Specific details on test material used for the study:
SMILES: CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C(=O)[O-].[Na+]
Key result
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction
Details on results:
Biowin1 (Linear Biodeg Probability): 0.9645
Biowin2 (Non-Linear Biodeg Probability): 0.9967
A Probability Greater Than or Equal to 0.5 indicates --> Biodegrades Fast
A Probability Less Than 0.5 indicates --> Does NOT Biodegrade Fast

Biowin3 (Survey Model - Ultimate Biodeg): 2.8970
Biowin4 (Survey Model - Primary Biodeg): 4.0728
Result Classification: 5.00 -> hours 4.00 -> days 3.00 -> weeks
(Primary & Ultimate) 2.00 -> months 1.00 -> longer

Biowin5 (MITI Linear Biodeg Probability): 0.8471
Biowin6 (MITI Non-Linear Biodeg Probability): 0.8776
A Probability Greater Than or Equal to 0.5 indicates --> Readily Degradable
A Probability Less Than 0.5 indicates --> NOT Readily Degradable

Biowin7 (Anaerobic Linear Biodeg Prob): 0.9146
A Probability Greater Than or Equal to 0.5 indicates --> Biodegrades Fast
A Probability Less Than 0.5 indicates --> Does NOT Biodegrade Fast
Validity criteria fulfilled:
not applicable
Interpretation of results:
readily biodegradable
Conclusions:
Sodium isostearoyl lactylate (ISL) is predicted to be readily biodegradable by the (Q)SAR model BIOWIN v4.10.
Executive summary:

Sodium isostearoyl lactylate (ISL) is predicted to be readily biodegradable by the (Q)SAR model BIOWIN v4.10.

Description of key information

Sodium isostearoyl lactylate (ISL) is readily biodegradable (QSAR prediction, BIOWIN 4.10).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:
freshwater

Additional information