Registration Dossier
Registration Dossier
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EC number: 203-744-6 | CAS number: 110-18-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.021 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.021 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.002 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 5.67 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.092 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.009 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.006 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Experimental data investigating the ecotoxicity of TMEDA are available from a short-term fish toxicity study, a short-term Daphnia toxicity study and an algal growth inhibition study. Long-term ecotoxicity data are not available for fish or aquatic invertebrates. The algal growth inhibition study showed the most conservative toxicity data from these studies, having resulted in a 72-h ErC50 value of 20.5 mg/L and a 72-h NOEC of 0.954 mg/L.
A ready biodegradability study according to the OECD guideline 301B is available, the results of which concluded that TMEDA is not readily biodegradable.
Based on the above information, self-classification would assume that TMEDA is not classified for acute aquatic toxicity under the CLP regulation (Regulation (EC) No 1272/2008) but is classified as acute aquatic toxicity, Category 2 (H401) under the Globally Harmonised System (GHS), and is also classified as chronic aquatic toxicity, Category 2 (H411) under both the CLP regulation and GHS. However, a harmonised classification (Annex VI) is available for TMEDA which concludes that the substance is not classified for either acute or chronic aquatic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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