Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.021 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.021 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.002 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
5.67 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.092 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.009 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.006 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Experimental data investigating the ecotoxicity of TMEDA are available from a short-term fish toxicity study, a short-term Daphnia toxicity study and an algal growth inhibition study. Long-term ecotoxicity data are not available for fish or aquatic invertebrates. The algal growth inhibition study showed the most conservative toxicity data from these studies, having resulted in a 72-h ErC50 value of 20.5 mg/L and a 72-h NOEC of 0.954 mg/L.

A ready biodegradability study according to the OECD guideline 301B is available, the results of which concluded that TMEDA is not readily biodegradable. 

Based on the above information, self-classification would assume that TMEDA is not classified for acute aquatic toxicity under the CLP regulation (Regulation (EC) No 1272/2008) but is classified as acute aquatic toxicity, Category 2 (H401) under the Globally Harmonised System (GHS), and is also classified as chronic aquatic toxicity, Category 2 (H411) under both the CLP regulation and GHS. However, a harmonised classification (Annex VI) is available for TMEDA which concludes that the substance is not classified for either acute or chronic aquatic toxicity.