Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 26, 2009 - November 29, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Test facility ISO 9000 series accredited.
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Polynt lot no. T101208268
- Production date: 24 Sep 2008
- Expiration date of the lot: 24 Sep 2009

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Keep container tightly closed. Keep in a dry, cool and well ventilated place.
- Storage at testing facility: 5 years.
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
1.4
Temp.:
40 °C
pH:
7.1
Conclusions:
The partition coefficient of diethyl succinate item was determined to be: Log10 Pow= 1.4 at T= 40°C and pH= 7.1
Executive summary:

The partition coefficient of diethyl succinate item was determined to be: Log10 Pow= 1.4 at T= 40°C and pH= 7.1

Description of key information

Partition coefficient (log Pow): 1.4 at 40 deg C and pH 7.1

Key value for chemical safety assessment

Log Kow (Log Pow):
1.4
at the temperature of:
40 °C

Additional information

The octanol-water partition coefficient of diethyl succinate, determined according to OECD/EU methods, was Log10Pow = 1.4 at 40 deg C and pH 7.1