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EC number: 203-996-7 | CAS number: 112-67-4
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound palmitoyl chloride: No data available
Hydrolysis product palmitic acid: Readily biodegradable
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Parent compound palmitoyl chloride (CAS 112 -67 -4):
No experimental data are available for the parent compound. However, since the substance is known to hydrolyse very quickly to palmitic acid (CAS 57 -10 -3) and HCl (CAS 7647 -01 -0), the assessment of the biodegradability is based on the hydrolysis product palmitic acid (CAS 57 -10 -3). Palmitic acid is readily biodegradable (see below).
Hydrolysis product palmitic acid (CAS 57 -10 -3):
To assess the ready biodegradability of palmitic acid, a closed bottle test (BODIS test, guideline similar to OECD TG 301D) is available. As inoculum non-adapted activated sludge from a wastewater treatment plant treating predominantly domestic wastewater was used. After 28 days the degradation was 65 % based on BOD28/COD. (BASF AG, 1994, report no.: R9400080).
The result is supported by two calculations:
- CATALOGIC 301C v11.15 (OASIS Catalogic v5.13.1.156): 100 % degradation in 28 d (within applicability domain: 100%) - readily biodegradable
- CATALOGIC Kinetic 301F v13.16 (OASIS Catalogic v5.13.1.156): 81% degradation in 28 d (within applicability domain: 100%, 10d window kept) - readily biodegradable
As palmitic acid is hardly soluble in water (WS = 0.04 mg/L, Robb 1966, PhysProp database of EPI Suite v4.11) and highly adsorptive (see IUCLID Ch. 5.4.1), in addition to the test on ready biodegradability, a biodegradation test under anaerobic conditions was performed according to the ECETOC guideline. Under anaerobic conditions, palmitic acid was degraded to 77.3 % in 69 days, based on DOC removal (BASF AG, 1992, report no: 920143).
The results of a ring test optimizing the ECETOC guideline with palmitic acid as test substance is also available. The publication is of limited documentation. However, the mean degradation of valid data (n = 27) indicates a degradation of 72.2% for palmitic acid and therefore supports the biodegradability under anaerobic conditions (Pagga, 1993).
Conclusion:
Based on the available data, the parent compound palmitoyl chloride and its hydrolysis product palmitic acid are expected to be readily biodegradable.
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