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EC number: 946-682-1
CAS number: -
The registered substance is readily biodegradable and no transformation product was detected after 28 days. Therefore, the registered substance and the potentiel degradation product(s) are not considered persistent (P) in the environment.
Then, according to ECHA Guidance Chapter R.11 Version 3.0 (June 2017), the B-criterion is unlikely to be triggered for substances with a log Kow higher than 10. Indeed, for highly hydrophobic substances, like the registered substance with a log Kow value > 6, experimentally derived BCF values tend to decrease with increasing log Kow. This was confirmed with predicted BCF values, all comprised between 0.94 and 9.42 L/kg. The registered substance is not considered bioaccumulable (B) or very bioaccumulable (vB) (BCF < 2000). In addition, the registered substance presents no toxicity for mammals. The "No Observed Adverse Effect Level", NOAEL, was determined at the highest tested dose in the sub-acute and sub-chronic oral toxicity studies. This observation confirms the limited absorption and therefore the limited bioaccumulation of the registered substance.
Finally, no toxic effects were observed up to the highest loading rate of 10000 mg/L (or 10 mg/L in the chronic fish test) in experimental acute and chronic studies for the three aquatic trophic levels (fish, aquatic invertebrates and algae). The substance is not classified as carcinogenic, mutagenic, or toxic for reproduction according to Directive 67/548/EEC or carcinogenic, germ cell mutagenic, or toxic for reproduction according to Regulation EC No 1272/2008. In addition, there is no evidence of chronic toxicity, as identified by the classifications T, R48 or Xn, R48 according to Directive 67/548/EEC or specific target organ toxicity after repeated exposure according to Regulation EC No 1272/2008. Therefore, the registered substance is not toxic (T).
As the potentiel degradation product(s) of the registered substance are not considered Persistent in the environment, there is no need to assess whether the Bioaccumulation and/or Toxicity criterion is/are fulfilled, for the PBT Assessment.
In conclusion, the registered substance and the potentiel degradation product(s) could not be considered as a PBT or vPvB substances.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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