Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Acidic group (AR)NHCOR: pKa = 12.9
Basic groups 1,2,4-TRAZOLE: pKa = 1.4; (AR)NHCOR: pKa = - 3.6 (Perrin's calculation method)

Key value for chemical safety assessment

Additional information

In accordance with Regulation (EC) No 1907/2006, Annex XI, Section 1, this study not scientifically relevant: due to the chemical structure, no dissociation is to be expected under naturally relevant pH conditions.

Therefore the dissociation constant of 2-hexyldecanoic acid [4-(6-tert-butyl-7-chloro-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)phenylcarbamoyl]methylester (UM-235) were calculated by using Perrin's calculation method.