Registration Dossier
Registration Dossier
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EC number: 448-260-8 | CAS number: 379268-96-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 33.3 mg/kg food
- Assessment factor:
- 300
Additional information
Conclusion on classification
Classification related key information
Water solubility: < 0.004 mg/L (OECD 105)
Biodegradation in water: screening tests: 12 - 15% (ThCO2) in 28 days (OECD 301B)
Log Kow: 8.45
Acute aquatic toxicity
- to fish: No effects were observed in the range of the water solubility of the test substance (0.052 mg/L), Cyprinus carpio (EU Method C.1).
- to aquatic invertebrates: No effects were observed in the range of the water solubility of the test substance (0.044 mg/L), Daphnia magna (OECD 202).
- to algae: No effects were observed in the range of the water solubility of the test substance (0.031 mg/L), Selenastrum capricornutum (OECD 201).
Chronic aquatic toxicity:
- to fish: not available
- to aquatic invertebrates: not available
- to algae: No effects were observed in the range of the water solubility of the test substance (0.031 mg/L), Selenastrum capricornutum (OECD 201).
Classification justification according to CLP
UM-235 (2-hexyldecanoic acid[4-(6-tert-butyl-7-chloro-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)phenylcarbamoyl]methylester) is not toxic to aquatic organisms (fish, aquatic invertebrates, algae) in the range of its water solubility (0.031 to 0.052 mg/L). Nevertheless, since the substance is not rapidly biodegradable and exhibits a potential for bioaccumulation (log Kow 8.45), UM-235 is classified as environmental hazard Chronic Cat. 4 according to the regulation (EC) No. 1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2nd ATP)
Classification justification according to DSD
For fish, aquatic invertebrates and algae, no toxic effects were observed in the range of the water solubility of UM-235 (0.031 to 0.052 mg/L). Based on the data above, the substance is considered to have a substantial potential for bioaccumulation and is not rapidly degradable. Therefore, UM-235 is classified as environmental hazard R53 according to the Directive 67/548/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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