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EC number: 218-780-8 | CAS number: 2234-16-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27 March 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- 1.4.4. Method according to Siwoloboff
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- method according to Siwoloboff
- Remarks:
- Capillary tube in heated metal block
- Key result
- Boiling pt.:
- ca. 255.7 °C
- Atm. press.:
- ca. 1 001.7 hPa
- Conclusions:
- The boiling point of the test item was observed at temperature of 255.7 ± 0.5 °C under atmospheric pressure of 1001.7 hPa.
- Executive summary:
Determination of the boiling point was performed in accordance with the OECD No. 103, EEC A.2 method and with GLP.The boiling point was determined using capillary tube in metal block (1.4.4. Method according to Siwoloboff), which is in conformity with the OECD Guideline for Testing of Chemicals no 103 “Boiling point”. The capillary tube in heated metal block method was used with the BÜCHI Melting Point B-565 apparatus. The measurements were performed in three samples of the test item. The boiling point of the test item was observed at temperature of 255.7 ± 0.5 °C under atmospheric pressure of 1001.7 hPa.
Reference
The preliminary study and final measurements were performed under atmospheric pressure of 1001.7 hPa.
The preliminary study was carried out in order to determine the boiling temperature range for 1-(2,4-dichlorophenyl)ethan-1-one. The average value of an initial boiling point was approximately 250.0 °C when heated at 10.0 °C per minute in the range of 120-400 °C.
Observed values of the boiling point of the test item
Sample |
Boiling temperature, °C |
Boiling point, ºC |
1 |
255.7 |
256.3 |
2 |
254.8 |
255.4 |
3 |
254.7 |
255.4 |
Average value ± standard deviation, °C |
255.1 ± 0.6 |
255.7 ± 0.5 |
Atmospheric pressure, hPa: 1001.7
Description of key information
Key study: According to OECD TG 103 and EEC method A.2. GLP study. The boiling point of the test item was observed at temperature of 255.7 ± 0.5 °C under atmospheric pressure of 1001.7 hPa.
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 255.7 °C
Additional information
Key study: The determination of the boiling point was performed in accordance with OECD No. 103, EEC A.2 method and with GLP.The boiling point was determined using capillary tube in metal block (1.4.4. Method according to Siwoloboff), which is in conformity with the OECD Guideline for Testing of Chemicals no 103 “Boiling point”. The capillary tube in heated metal block method was used with the BÜCHI Melting Point B-565 apparatus. The measurements were performed in three samples of the test item. The boiling point of the test item was observed at temperature of 255.7 ± 0.5 °C under atmospheric pressure of 1001.7 hPa.
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