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Administrative data

Endpoint:
oxidising solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2.3.2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.17 (Oxidising Properties (Solids))
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one
EC Number:
608-748-5
Cas Number:
324763-46-4
Molecular formula:
C25 H39 N3 O5
IUPAC Name:
(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one

Results and discussion

Any other information on results incl. tables

According to the guideline, a substance is considered to be oxidizing when the burning rate of a mixture of the test substance and cellulose is higher or equal to the maximum burning rate of a reference mixture of cellulose and barium nitrate.

Examination of the molecular structure of the major component, present for 95.93% in test substance, establishes beyond reasonable doubt that the component is incapable of burning, when mixed with cellulose, at a higher or equal rate compared with the maximum burning rate of a reference mixture of cellulose and barium nitrate. The major component does not contain any group that might act as an oxidizing agent. The oxygen atoms that are present in the test substance are all bonded to carbon, which indicates that the molecule is oxygen-deficient. This is also the case for the stereoisomer, present for 3.4% in the test substance. Components present for < 1% were not taken into account.

Based on the composition of test substance and the molecular structures, it was concluded that the test substance has no oxidizing properties.

Applicant's summary and conclusion

Interpretation of results:
other: no oxidising properties
Remarks:
Migrated information
Conclusions:
the test substance has no oxidizing properties.

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