Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-076-8 | CAS number: 7785-23-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
The most sensitive endpoint is a 10-day NOEC (growth) for Hyalella azteca of 0.012 g Ag/kg dry weight (Call et al., 2006). This value was used to derive the sediment PNEC. An assessment factor of 10 was applicable, and the value was normalised to 5 % organic content to give the derived PNEC of
438.13 mg/kg dw.
Key value for chemical safety assessment
Additional information
In freshwater sediments spiked with silver nitrate, a high proportion of the dissolved silver fraction was not readily bioavailable to cause lethality to dipteran insect larvae (Call et al., 1999). Porewater concentrations of dissolved silver that killed 50% of the larvae were up to 275 times greater than the 10-day water only LC50 value of 57 µg/L, indicating that most of the dissolved fraction was not readily bioavailable to cause death. The 10-day LC50 values for Chironomus tentans, based upon nominal additions of Ag to sediments, were 2.75 and 1.17 g Ag/kg dry sediment. The lowest NOEC for growth was 0.2 g Ag/kg dry sediment.
Hyalella azteca held on sediments containing as much as 753 mg Ag/kg dw, as silver sulphide, for 10 days had normal growth and survival (Hirsch, 1998). No significant effect was observed on the growth of oligochaetes (Lumbriculus variegatus) exposed to laboratory-spiked sediments containing 444 mg Ag kg dw, as silver sulphide for 28 days (Hirsch, 1998).
Hyalella azteca exposed to Ag as AgNO3 over a 10-day period in two lake sediments resulted in 10-day LC50s of 0.084 g Ag/kg and 2.98 g Ag/kg dry sediment for sediment with a lower quantity of total Ag-binding ligands and a greater quantity of total Ag-binding ligands respectively (Call et al., 2006). The NOEC for growth in the former was 0.012 g Ag/kg dry sediment. These results demonstrate the differing Ag binding capacities of sediments. The sediment with the lower quantity of Ag-binding ligands was sandy (95.3%) with a low level of organic carbon (0.29% TOC). In contrast, the other sediment contained a greater proportion of small-grained particles (59% silt; 11.2% clay) and a higher lever of organic carbon (2.5% TOC).
As discussed above, sediment physicochemistry can affect the toxicity of silver in sediments. Berry et al. (1999) exposed the marine amphipod Ampelisca abdita for 10 days to two marine sediments with different amounts of acid-volatile sulphide spiked with silver (Sediment 1: 2.7 – 4415 mg silver/kg dw, Sediment 2: 2.7 – 72,770 mg silver/kg dw). The EC10 values for these two sediments were 4415 and 6626 mg/kg, respectively. In general, sediment treatments with an excess of acid-volatile sulphide (AVS) relative to simultaneously extracted metal were not toxic to marine amphipods.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.