Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
55 mg/kg bw/day
Study duration:
Quality of whole database:
The NOAEL of the base form of MBB was calculated from the sulfate form NOAEL (90 mg/kgbw/d).

Additional information

Justification for selection of repeated dose toxicity via oral route - systemic effects endpoint:
Although the test was performed on the sulfate form, the toxicological data generated at pH > 4.5 are directly applicable to MBB (see speciation document in section 1.4)

Justification for classification or non-classification

The substance is not classified for repeated toxicity effects.