Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Dodecane-12-lactam, manufacturing of, by-products from, distillation residues has been shown to be no toxic to fish and algae and harmful to daphnia in several acute studies (fish: 96 h LC50-96h > 100 mg/L (nominal value); algae: EC50-72h > 100 mg/L (nominal value): daphnids: EC50-48h = 33.67 mg/L (measured concentration).


As no long-term toxicity studies are available (except algae study), the PNEC can be determined using the lowest short-term result by applying an uncertainty factor of 1000. The resulting PNEC would be 33.67 µg/L.