Registration Dossier
Registration Dossier
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EC number: 411-200-6 | CAS number: 14657-64-8 FYROL 3-HPP; HIRETAR-205; PHOSGARD PF 100
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: ECHA inquiry result
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 84/449/EWG, B.3
- GLP compliance:
- yes
- Limit test:
- yes
Test material
- Reference substance name:
- 3-(hydroxyphenylphosphinyl)propanoic acid
- EC Number:
- 411-200-6
- EC Name:
- 3-(hydroxyphenylphosphinyl)propanoic acid
- Cas Number:
- 14657-64-8
- Molecular formula:
- C9H11O4P
- IUPAC Name:
- 3-[hydroxy(phenyl)phosphoryl]propanoic acid
Constituent 1
Test animals
- Species:
- other: rat, Sprague Dawley
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- other: Mit Wasser angefeuchtet "ENGLISH" Moistered with water
- Duration of exposure:
- 24 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: Alle Tiere überlebten die Studie. Es wurden keine klinischen Symptome festgestellt. Im Vergleich mit der Kontrollgruppe konnten keine Effekte beobachtet werden. "ENGLISH" Mortality: There were no deaths. CLINICAL
- Gross pathology:
- Effects on organs:
Es wurden keine Effekte beobachtet.
"ENGLISH"
No findings were observed. - Other findings:
- Signs of toxicity (local):
Es wurden keine lokalen Effekte beobachtet.
"ENGLISH"
No local signs of toxicitiy were observed during
the study period.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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