Cyclopentadecanone

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12 December 2015 - 21 April 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

61 °C

Atm. press.:

>= 1 002 - <= 1 006 hPa

TGA EXPERIMENT (PRELIMINARY TEST)

From 175°C upwards the weight of the sample decreased significantly. At 271°C the sample weight had decreased by 25%. After the experiment it was observed that the test item was evaporated from the sample container.

 

DSC EXPERIMENT 1

An endothermic peak between 25°C and 75°C was observed. The extrapolated onset temperature of the peak was 60.88°C. The effect was most likely obtained due to melting of the test item. Another endothermic effect was observed between 200°C and 325°C. The extrapolated onset temperature of the peak was 245.89°C. The effect was most likely obtained due to boiling of the test item. After the experiment it was observed that the test item had evaporated from the sample container.

DSC EXPERIMENT 2

With the first heating the extrapolated onset temperature of the melting peak was 61.26°C. During cooling an exothermic peak was observed between 45°C and 55°C. The effect was obtained due to crystallization of the test item. With the second heating an extrapolated onset temperature of 59.38°C was obtained. The results demonstrated that the endothermic effect was due to melting of the test item. Another endothermic effect was observed between 200°C and 325°C. The extrapolated onset temperature of the peak was 245.78°C. The effect was most likely obtained due to boiling of the test item. After the experiment it was observed that the test item had evaporated from the sample container.

DSC EXPERIMENT 3

The extrapolated onset temperature of the melting peak was 61.52°C. The extrapolated onset temperature of the boiling peak was 320.68°C. The endothermic peak shifted to higher temperatures. It demonstrated that boiling of the test item was the reason for the endothermic effect. After the experiment it was observed that the test item had evaporated from the sample container.

DSC EXPERIMENT 4

Similar results to Experiment 1 were obtained. The extrapolated onsets of the melting and boiling peaks were (respectively) 61.35°C and 245.38°C. After the experiment it was observed that the test item had evaporated from the sample container.

 

The melting temperature was determined as the average obtained from Experiment 1 (60.88°C), Experiment 2 first heating (61.26°C), Experiment 3 (61.52°C) and Experiment 4 (61.35°C).

Conclusions:

The melting temperature of the substance Cyclopentadecanone was determined to be 61°C.

Executive summary:

Differential Scanning Calorimetry (DSC) experiments were performed in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200.

The melting temperature of the substance Cyclopentadecanone was determined in quadruplicate obtaining a mean value of 61°C.

Description of key information

The melting temperature of the substance was determined to be 61°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

61 °C

Additional information

Determined using Differential Scanning Calorimetry (DSC) experiments in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200.