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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

As no valid study is available for the aquatic toxicity of Alcohols, lanolin, distn. residues (CAS No. 90622-40-5) to aquatic organisms, read-across to the structurally and physico-chemically related substance Alcohols, lanolin (CAS No. 8027-33-6) was conducted, in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances.

For the acute toxicity of the source substance Alcohols, lanolin (CAS No. 8027-33-6) to aquatic organisms, studies for three different trophic levels are available. For all three trophic levels (fish, aquatic invertebrates and algae) no toxicity within the range of water solubility was observed.

For the long-term effects of the source substance Alcohols, lanolin (CAS 8027-33-6) to aquatic organisms studies are available for unicellular freshwater microalgae and daphnia. In both the algae and daphnia study, no long-term effects were observed up to limit of water solubility (< 0.1 mg/L).

There are no long-term fish studies available for Alcohols, lanolin, distn. residues (CAS No. 90622-40-5). Based on the acute values, fish cannot be identified as the most sensitive taxonomic group. According to the “Guidance on information requirements and chemical safety assessment Chapter R.7b: Endpoint specific guidance, R.7.8.5.3” (ECHA, 2016), long-term testing of fish should only be conducted if it represents the most sensitive taxonomic group. The Guidance states that if invertebrates are likely to be more sensitive than fish and algae or the relative sensitivity of invertebrates cannot be predicted, long-term testing on Daphnia sp. should be preferred instead of fish. Hence, for animal welfare, no further long-term fish tests were proposed.

There are no studies on toxicity to microorganisms available for Alcohols, lanolin, distn. residues (CAS No. 90622-40-5). However, in accordance with Annex VIII, column 2, 9.1.4 of Regulation (EC) No. 1907/2006, activated sludge respiration inhibition testing is not required since the substance is highly insoluble in water.

Additionally, a substance can be assumed to be not inhibitory to aquatic microorganisms, if in the toxicity control of a ready biodegradation test, more than 35% degradation removal occurred within 14 days (OECD guidance 301). For the structure related Alcohols, lanolin (CAS No. 8027-33-6) which was used in a read-across approach to cover the biodegradability of Alcohols, lanolin, distn. residues (CAS No. 90622-40-5), a biodegradation test according to OECD guideline 301B is available. This test includes a toxicity control containing of about 15 mg/L of test substance. The toxicity control attained 49% degradation after 14 days of incubation. Hence, the substance was not toxic to aquatic microorganisms in the toxicity control and the highest test concentration of 15 mg/L can be determined as NOEC. The degradation process in sewage treatment plants is not expected to be inhibited by the test item.

General conclusion

No effects on aquatic organisms were observed up to the limit of water solubility on all three trophic levels (fish, daphnia, and algae) in both the short-term as well as the long-term tests. Furthermore, no toxic effects on microorganisms are expected.