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EC number: 200-087-7 | CAS number: 51-28-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Other distribution data
Administrative data
- Endpoint:
- other distribution data
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data have been obtained from secondary source.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Toxicological Profile for dinitrophenol
- Author:
- M. Olivia Harris, M.A; James J. Corcoran, Ph.D. (peer rewied by Dr. Martin Alexander; Dr.Leon Koller; Dr.Norman Trieff)
- Year:
- 1 995
- Bibliographic source:
- U.S Department of Health and human Services, Public Health Service Agency for Toxic Substances and Disease Registry
- Reference Type:
- review article or handbook
- Title:
- Studies on photochemical reaction of air pollutants: X. Identification of nitrophenols in suspended particulates.
- Author:
- Nojima K, Kawaguchi A, Ohya T, et al.
- Year:
- 1 983
- Bibliographic source:
- Chem Pharm Bull 31: 1047-1051, 1983
Materials and methods
- Principles of method if other than guideline:
- Gas chromatographic (GC) and high-performance liquid chromatographic (HPLC) columns are often used as the final step towards resolution with a a variety of detectors to quantify dinitrophenols; The method consisted in the detection of both 2,4- and 2,6-DNP in particulate matter in air in Yokohama, Japan for 5 days.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,4-dinitrophenol
- EC Number:
- 200-087-7
- EC Name:
- 2,4-dinitrophenol
- Cas Number:
- 51-28-5
- Molecular formula:
- C6H4N2O5
- IUPAC Name:
- 2,4-dinitrophenol
Constituent 1
Results and discussion
Any other information on results incl. tables
The reported concentration ranges of 2,4 -dinitrophenol in particulate matter in air in Yokohama, Japan, during 5 days were 2.4-12 μg/g particulates, that are indirect indications of the presence of these compounds in the air.
The observation that dinitrophenols are found at least partly in the particulate-sorbed state in the air indicates that their bioavailability from air is < 100%.
Applicant's summary and conclusion
- Conclusions:
- The reported concentration ranges of 2,4 -dinitrophenol in particulate matter in air in Yokohama, Japan, during 5 days were 2.4-12 μg/g particulates, that are indirect indications of the presence of these compounds in the air.
The observation that dinitrophenols are found at least partly in the particulate-sorbed state in the air indicates that their bioavailability from air is < 100%. - Executive summary:
Data have been obtained from secondary source that mentions Nojima K, Kawaguchi A, Ohya T, et al. 1983. Studies on photochemical reaction of air pollutants: X. Identification of nitrophenols in suspended particulates. Chem Pharm Bull 31: 1047-1051.
The method consisted in the detection of both 2,4- and 2,6-DNP was done by GC in particulate matter in air in Yokohama, Japan for 5 days.
Because underivatized nitrophenols are irreversibly sorbed on active sites of GC column materials, it may be necessary to derivatize the compounds to increase their volatility to enhance elution from the GC column.
The reported concentration ranges of 2,4 -dinitrophenol in particulate matter in air in Yokohama during the 5 days were 2.4-12 μg/g particulates, that are indirect indications of the presence of these compounds in the air.
The observation that dinitrophenols are found at least partly in the particulate-sorbed state in the air indicates that their bioavailability from air is < 100%.
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